Skin Cancer

While melanoma, psoriasis, rosacea, and allergies are conditions that commonly show up on the skin, there are systemic diseases and disorders that may also manifest in your skin. Oftentimes, the skin can give clues to conditions that affect other parts of your body. The following are several medical conditions that may show up on your skin before you even realize you have been afflicted by a disease.

10. Addison’s Disease

Addison's Disease

Addison’s disease occurs when your adrenal glands do not produce enough cortisol or aldosterone hormones. This rare condition can be life-threatening, as the body requires cortisol to turn food into energy, respond to stress, and maintain healthy immune function. The hormone aldosterone is necessary for maintaining a proper balance of sodium and potassium levels and keeping your blood pressure regulated. One of the early signs of Addison’s disease may be a darkening of the skin, called hyperpigmentation. Other signs are extreme tiredness, loss of appetite, low blood pressure, and low blood sugar.

9. Celiac Disease

Celiac Disease

Dermatitis herpetiformis is a severe, itchy, blistery skin rash that is a sign of celiac disease. Not all celiac patients have this skin condition, which is a part of the immune system’s abnormal response to gluten. In fact, only 15-25% of celiac patients experience this rash, which may be confused with bug bites or allergic reactions. Dermatitis herpetiformis typically affects the skin of the elbows, knees, and buttocks. Men are more likely than women to suffer from this disorder, which is treated with topical antibiotics followed by the avoidance of gluten.

Related: 7 Most Common Symptoms of Diabetes


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