Adenocarcinoma very rarely develops from the sweat glands in the penis. Adenocarcinoma is most commonly found in lung, prostate, pancreatic, esophageal, and colorectal cancers. Penile adenocarcinoma may look like carcinoma in situ.
Soft tissue sarcoma encompasses tissues that develop in soft tissues such as muscle, tendons, fat, lymph nodes, blood vessels, and nerves. Soft tissue sarcomas are mainly found in the arms, legs, and torso. On rare occasions, they can develop from the blood vessels or connective tissues of the penis.
5. Symptoms of Penile CancerRelated: 11 Early Signs of Cancer Men Should Never Ignore
Changes in the skin of the penis are often the first indication that something is awry. Penile cancer lesions may appear on the head (glans) of the penis, on the shaft of the penis, or on the foreskin of uncircumcised men. One warning sign is when an area of skin becomes thicker than the surrounding areas or changes in color. You may notice a tumor, a lump, or an open sore. Skin growths can appear as crusty bumps or flat brown nodules. A rash, foul-smelling discharge, or bleeding under the foreskin of uncircumcised men is also a signal to seek medical attention.