8. Infection

Bacterial Infection

An infection of the skin or tissues of your feet may cause swelling and inflammation as your immune system kicks into gear. Patients with diabetic nephropathy may be more prone to foot sores or ulcers, which can become infected. According to APMA, diabetic patients are susceptible to foot ulcers due to decreased sensation in the extremities, poor circulation, and injury.

7. Kidney Failure

Kidney Disease

Swollen ankles, puffy eyes, dry skin, itchiness, and fatigue are all symptoms of kidney disease. According to the National Kidney Foundation, the main causes of chronic kidney disease (CKD) are diabetes and high blood pressure. Risk factors for CKD also include a family history of the disease and advanced age. Complications of CKD include high blood pressure, anemia, weakness, and nerve damage.

6. Liver Cirrhosis

Liver Cirrhosis

Cirrhosis refers to a condition in which healthy liver tissue is replaced with scar tissue. As the liver becomes damaged and unable to function, the body may retain sodium and water. This causes swelling in the foot, leg, or abdomen. According to the Cleveland Clinic, conditions such as alcoholism, cystic fibrosis, autoimmune hepatitis, diabetes, and viral infections may cause cirrhosis.



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