13. Antibiotics


Moderate amounts of alcohol should not interact with the majority of antibiotics. However, there are some antibiotics that can cause severe reactions when combined with alcohol. Sulfamethoxazole/trimethoprim is an antibiotic combination that can react with alcohol to cause nausea, vomiting, and increased heart rate. Metronidazole is another antibiotic that can cause severe headaches, nausea, stomach cramping, and flushing when alcohol is consumed. The University of Michigan School of Medicine warns that alcohol should be avoided for three days following the use of metronidazole.

12. Antidepressants


Medications that affect your central nervous system can be affected by alcohol consumption. Many antidepressant medications can cause excess drowsiness, dizziness, or confusion when combined with alcohol use. In addition, combining them with alcohol can increase the risk of accidental overdose. A specific class of antidepressants called monoamine oxidase inhibitors (MAOIs) can cause severe heart issues when alcohol is consumed. MAOIs can combine with the tyramine found in certain alcoholic beverages and raise your blood pressure to dangerously high levels.

11. Anxiety Medications

Anxiety Medication

Medications that decrease anxiety do so by working on the central nervous system. Benzodiazepines such as Ativan (lorazepam), Klonopin (clonazepam), and Valium (diazepam) decrease anxiety through their effects on the neurotransmitter GABA in the brain. Taken with alcohol, they can increase drowsiness, interfere with motor control, and slow down breathing. Combining alcohol with anxiety medications can also result in memory and cognitive issues.

Related: 10 Medications That You Shouldn’t Suddenly Stop Taking


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