4. Staphylococcal Scalded Skin Syndrome (SSSS)

Staphylococcal Scalded Skin Syndrome

SSSS is most commonly seen in children under the age of five. A weakened immune system or chronic kidney disease may also increase an individual’s risk of this rare condition. Johns Hopkins Medicine lists irritability, fatigue, fever, red skin, and painful, fluid-filled blisters as symptoms of this disease. Furthermore, the top layer of the affected child’s skin may peel away in large sheets. Treatment usually consists of antibiotics, IV fluids, tube feedings, pain medications, and wound care.

3. Stevens-Johnson Syndrome (SJS)

Stevens Johnson Syndrome

SJS is a rare skin condition resulting in a rash that forms blisters and then peels away. The Cleveland Clinic reports that patients with this condition are often treated in the burn units of hospitals. SJS may occur as a reaction to medications. In other cases, SJS appears to be an inherited condition. When a medication triggers SJS, that medicine is discontinued. Treatment may then consist of IV fluids, wound care, tube feedings, and antibiotics. Complications of SJS can include pneumonia, sepsis, organ failure, shock, and death.

2. Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

The Cleveland Clinic reports that some health experts believe SJS and TEN to be one disease, while others consider them to be different conditions. In any case, TEN is usually a more severe condition. Medscape states that SJS usually affects less than 10% of an afflicted person’s body surface, while TEN involves more than 30% of a person’s body surface. TEN also carries a higher risk of death. Treatment for TEN is similar to that for SJS, with admittance to the burn unit of a hospital. Here medical personnel can provide fluids, tube feedings, antibiotics, and extensive wound care.

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