Obstacles in Alzheimer’s Treatment
There are two major obstacles in the search for a definitive treatment for Alzheimer’s. The first one is the lack of information about the underlying biology of this condition. We do not know what leads to the toxic build up in the brain or why the progression of the disease varies from one person to another.
The second significant challenge is that a method has to be developed that allows drugs to overcome the blood-brain barrier. This barrier keeps the brain safe from pathogens and toxins that might be found in blood. It has been designed in such a way that it effectively bars foreign substances from reaching the brain. However, the disadvantage is that it also prevents most drugs from accessing the brain.
Major Symptoms of Alzheimer’s
The symptoms of Alzheimer’s can develop over many years and by the time of diagnosis, the brain is likely to have experienced neurodegenerative changes. Also, Alzheimer’s may be present alongside other types of dementia. Here are some symptoms that might indicate the onset of Alzheimer’s. These can vary from person to person and it is important to consult a doctor if you or a loved one experiences any of these symptoms.
Challenges with Memory and Mental Agility
Fading Memory That Impacts Everyday Life: The most common symptom is a weakening memory. The inability to remember things just learned, losing track of significant dates and days, and seeking the same information repeatedly are some warning signs. If the person has to depend on memory aids or members of the family for assistance in recalling stuff, you might be right to start getting concerned.
Difficulty Solving Problems and Making Plans: It may be hard to make plans and to keep appointments. They might find it difficult to monitor bills and handle numbers in general. On an average day, they might find themselves incapable of following a recipe though it is something they have used many times previously.
Inability to Complete Regular Tasks: Simple things such as traveling to the place of work or recalling the rules of a favorite board game might become cumbersome. The patient might misplace belongings often and then be unable to retrace their actions and get them back. Blaming others for stealing their things is also a symptom of this condition and one that can get worse with time.
Losing Track of Time and Location: Forgetting the way to one’s home or office, finding oneself in a strange place and not knowing how they got there, frequently being disoriented about whereabouts, are all signs that there might be a problem that needs medical attention.