5. Types of Vitamin D
There are several forms of vitamin D within the human body. Your physician will use the complete total of the number of metabolites to check your vitamin D levels. The body converts what is considered a prohormone into a continually active form of vitamin D that the body can use.
Interestingly, 99 percent of metabolites of vitamin D that are found in the blood bind to proteins and only a very minuscule amount becomes active biologically. It appears that the free, active types of vitamin D are what is being used to predict possible current and future health disorders, and not the total levels of vitamin D in the body.
4. Looking at 25-hydroxyvitamin D Levels
In the European Male Aging Study, researchers gathered in-depth data from 1,970 men aged 40 to 79 years old between 2003 and 2005. After gathering the free metabolites of vitamin D, they then compared the levels of both free and total vitamin D in the men’s bods to their health status. They also factored in age, lifestyle, and body mass index (BMI).
The findings of the research celery show that free and bound vitamin D metabolites show a far higher risk of death. The free 25-hydroxyvitamin D pointed towards future health problems instead of free 1,25-dihydroxyvitamin D.
Dr. Antonio states the following, “These data further confirm that vitamin D deficiency is associated with a negative impact on general health and can be predictive of a higher risk of death.”
One stumbling block about the study was it was unable to obtain the cause of death of the participants who ended up dying in some situations. The inability to gain such insight makes it more difficult to determine the underlying mechanism.Related: Vitamin D Deficiency Linked to Many Diseases