3. Vitamin B12 and Vitamin D Deficiencies

Vitamin Deficiencies

Soy contains B12 analogs, which means that tofu has compounds that resemble vitamin B12. However, the B12 analogs cannot be used by the body in the same way in which B12 is used, which is why foods containing soy can contribute to vitamin B12 deficiency, especially among people who avoid animal proteins such as vegetarians and vegans. Additionally, soy foods like tofu also increase the body’s vitamin D requirements, which ultimately means that eating tofu can cause vitamin D deficiency.

Related: 12 Signs and Symptoms You Need More Vitamin B12

2. Digestive Difficulty

Digestive Difficulty

Unfermented soy products such as tofu contain strong enzyme inhibitors, which block the pancreatic enzyme trypsin, along with proteolytic enzymes needed for proper protein digestion. Not only does it disrupt a healthy digestive process, but it also causes pancreatic problems. The blocking of these enzymes can cause indigestion, gas, bloating and a whole set of gastrointestinal issues.

1. Potential Heart Issues

Heart Issues

Although tofu is commonly labeled as a heart-healthy alternative to animal proteins, there are studies that debunk these claims. In one animal subject study, researchers looked at the effect of a soy diet on hypertrophic cardiomyopathy (HCM), a condition where the heart muscles become abnormally thick, making it difficult for the heart to pump blood. A study published in the Journal of Clinical Investigation found that mice who were fed a soy diet exhibited significantly worse HCM than mice fed a soy-free (milk protein) diet. Ultimately, the study found that a diet rich in soy could have profound negative effects on the heart.

Related: Symptoms and Risk Factors of Vitamin D Deficiency


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